Breakthrough Bleeding in Hemophilia a Patients on Prophylaxis
نویسندگان
چکیده
منابع مشابه
Athletic participation in severe hemophilia: bleeding and joint outcomes in children on prophylaxis.
OBJECTIVES We sought to determine joint outcomes relative to impact level of athletic participation among school-aged children who had hemophilia and were taking prophylactic factor replacement, as well as to investigate prognostic factors for joint outcomes. METHODS School-aged boys with severe hemophilia A or B at a single center were included in the study. Clinical data on baseline joint s...
متن کاملBleeding in carriers of hemophilia.
A wide range of factor VIII and IX levels is observed in heterozygous carriers of hemophilia as well as in noncarriers. In female carriers, extreme lyonization may lead to low clotting factor levels. We studied the effect of heterozygous hemophilia carriership on the occurrence of bleeding symptoms. A postal survey was performed among most of the women who were tested for carriership of hemophi...
متن کاملOptimization of prophylaxis for hemophilia A
BACKGROUND & AIMS Prophylactic injections of factor VIII reduce the incidence of bleeds and slow the development of joint damage in people with hemophilia. The aim of this study was to identify optimal person-specific prophylaxis regimens for children with hemophilia A. METHODS Analytic and numerical methods were used to identify prophylaxis regimens which maximize the time for which plasma f...
متن کاملOral contraceptives and breakthrough bleeding: what patients need to know.
I n 1982, more than 20% of women surveyed in a nationally representative sample had discontinued oral contraceptives (OCs) on their own or at the recommendation of their physician due to bleeding or spotting. Sadly, the percentage today has not decreased much. Understandable concern, embarrassment, and annoyance lead these women to abandon OCs. What they often don’t know, though, is that breakt...
متن کاملEffects of coagulation factor concentrate prophylaxis in moderate and severe hemophilia A patients at a single hemophilia center in Korea
PURPOSE The aim of this study was to investigate prophylactic treatment effects in Korean patients with severe hemophilia A. METHODS A prospective study of 32 severe hemophilia A patients was conducted with the approval of the Institutional Review Board at the Eulji University Hospital. Two patients received primary prophylaxis; whereas, the other 30 patients were divided into 2 groups-second...
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ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v128.22.2581.2581